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- Title
Predictive value of C-reactive protein/albumin ratio for no-reflow in patients with non-ST-elevation myocardial infarction.
- Authors
Tosu, Aydın Rodi; Çınar, Tufan; Kalyoncuoğlu, Muhsin; Biter, Halil İbrahim; Çaka, Sinem; Çakal, Beytullah; Selçuk, Murat; Belen, Erdal; Can, Mehmet Mustafa
- Abstract
Introduction: The focus of this research was to explore the link between CRP (C-reactive protein) /albumin ratio (CAR), a novel inflammatory response marker, and no-reflow (NR) phenomena in non-ST elevation myocardial infarction (non-STEMI) patients during percutaneous coronary intervention (PCI). Methods: The current study recruited 209 non-STEMI participants who underwent PCI. The patients were divided into two groups based on their post-intervention Thrombolysis in Myocardial Infarction (TIMI) flow grade; those with and without NR. Results: In all, 30 non-STEMI patients (6.9%) had NR after PCI. CAR values were substantially greater in the NR group. The CAR was identified to be a determinant of the NR (OR: 1.250, 95% CI: 1.033-1.513, P = 0.02), although CRP and albumin were not independently related with NR in the multivariate analysis. In our investigation, low density lipoprotein-cholesterol levels and high thrombus burden were also predictors of the occurrence of NR. According to receiver operating characteristic curve evaluation, the optimal value of CAR was > 1.4 with 60% sensitivity and 47% specificity in detecting NR in non-STEMI patients following PCI. Conclusion: To the best of knowledge, this is the first investigation to demonstrate that the CAR, a new and useful inflammatory marker, can be utilized as a predictor of NR in patients with non-STEMI prior to PCI.
- Subjects
C-reactive protein; ALBUMINS; HDL cholesterol; PREDICTIVE tests; PERCUTANEOUS coronary intervention; CONFIDENCE intervals; MULTIVARIATE analysis; THROMBOLYTIC therapy; TREATMENT effectiveness; DESCRIPTIVE statistics; NON-ST elevated myocardial infarction; ODDS ratio; DATA analysis software
- Publication
Journal of Cardiovascular & Thoracic Research, 2022, Vol 14, Issue 4, p214
- ISSN
2008-5117
- Publication type
Article
- DOI
10.34172/jcvtr.2022.30549