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- Title
Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implications.
- Authors
Yalta, Kenan; Yetkin, Ertan; Yalta, Tülin
- Abstract
In cardiooncology practice, "early cardiotoxicity" refers to an emerging subclinical myocardial dysfunction/injury in response to certain chemotherapeutic regimens. This condition can progress to overt cardiotoxicity in time and hence warrants proper and timely diagnostic and preventive strategies. Current diagnostic strategies for "early cardiotoxicity" are largely based on conventional biomarkers and certain echocardiography indices. However, a significant gap still exists in this setting, warranting further strategies to improve diagnosis and overall prognosis in cancer survivors. Copeptin (surrogate marker of the arginine vasopressine axis) might serve as a promising adjunctive guide for the timely detection, risk stratification, and management of early cardiotoxicity on top of conventional strategies largely due to its multifaceted pathophysiological implications in the clinical setting. This work aims to focus on serum copeptin as a marker of "early cardiotoxicity" and its general clinical implications in patients with cancer.
- Subjects
CARDIOTOXICITY; BIOMARKERS; MEDICAL care; CARDIOVASCULAR system; CANCER patients; RISK assessment; PEPTIDES; CANCER patient medical care; DISEASE management
- Publication
Balkan Medical Journal, 2023, Vol 40, Issue 2, p82
- ISSN
2146-3123
- Publication type
Article
- DOI
10.4274/balkanmedj.galenos.2023.2023-2-14