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- Title
Single Dose Methotrexate in Treatment of Ectopic Pregnancy: Review of 32 Case.
- Authors
Aybatlı, Aysun; Kaplan, Petek Balkanlı; Alicik, Mehmet; Sayın, Niyazi Cenk; Yüce, Mehmet Ali
- Abstract
Objective: To evaluate the efficacy of single dose intramuscular methotrexate in the treatment of ectopic pregnancy. Material and Methods: 32 patients who matched the inclusion criteria were enrolled. Success of treatment was defined as a resolution of ectopic pregnancy without performing surgical intervention. The cases in whom the treatment was successful and those that were not were compared for β-hCG values and clinical features. Results: IFhCG at diagnosis averaged 1293.9 mlU/ml. Of the 32 patients who received methotrexate, 26 were successfully treated. 23 patients (71.8%) received a single dose of methotrexate, 3 patients (9.3%) received an additional dose of methotrexate, 6 patients (18.7%) who had failed methotrexate required surgery for cure. The success rate of single-dose methotrexate was 79.3%. Conclusion: Our study shows that single dose systemic methotrexate treatment can be used as an option in unruptured pregnancies.
- Subjects
ECTOPIC pregnancy; METHOTREXATE; DRUG dosage; SURGERY; PREGNANCY
- Publication
Balkan Medical Journal, 2011, Vol 28, Issue 1, p10
- ISSN
2146-3123
- Publication type
Article
- DOI
10.5174/tutfd.2009.02161.1