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Context-Specific Stress Causes Compartmentalized SARM1 Activation and Local Degeneration in Cortical Neurons.
Published in:
Journal of Neuroscience, 2024, v. 44, n. 24, p. 1, doi. 10.1523/JNEUROSCI.2424-23.2024
By:
- Hinz, Flora I.;
- Villegas, Carmela Louise M.;
- Roberts, Jasmine T.;
- Heming Yao;
- Gaddam, Shreya;
- Delwig, Anton;
- Green, Samantha A.;
- Fredrickson, Craig;
- Adrian, Max;
- Asuncion, Raymond R.;
- Cheung, Tommy K.;
- Hayne, Margaret;
- Hackos, David H.;
- Rose, Christopher M.;
- Richmond, David;
- Hoogenraad, Casper C.
Publication type:
Article
Computationally Discovered Potentiating Role of Glycans on NMDA Receptors.
Published in:
Scientific Reports, 2017, p. 44578, doi. 10.1038/srep44578
By:
- Sinitskiy, Anton V.;
- Stanley, Nathaniel H.;
- Hackos, David H.;
- Hanson, Jesse E.;
- Sellers, Benjamin D.;
- Pande, Vijay S.
Publication type:
Article
Whole genome sequencing across clinical trials identifies rare coding variants in GPR68 associated with chemotherapy-induced peripheral neuropathy.
Published in:
Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01193-4
By:
- Khan, Zia;
- Jung, Min;
- Crow, Megan;
- Mohindra, Rajat;
- Maiya, Vidya;
- Kaminker, Joshua S.;
- Hackos, David H.;
- Chandler, G. Scott;
- McCarthy, Mark I.;
- Bhangale, Tushar
Publication type:
Article
Pannexin-1 Is Blocked by Its C-Terminus through a Delocalized Non-Specific Interaction Surface.
Published in:
PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099596
By:
- Dourado, Michelle;
- Wong, Evera;
- Hackos, David H.
Publication type:
Article
Correction to: Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel NaV1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers.
Published in:
2019
By:
- Rothenberg, Michael E.;
- Tagen, Michael;
- Chang, Jae H.;
- Boyce-Rustay, Janel;
- Friesenhahn, Michel;
- Hackos, David H.;
- Hains, Avis;
- Sutherlin, Dan;
- Ward, Michael;
- Cho, William
Publication type:
Correction Notice
Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel NaV1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers.
Published in:
Clinical Drug Investigation, 2019, v. 39, n. 9, p. 873, doi. 10.1007/s40261-019-00832-2
By:
- Rothenberg, Michael E.;
- Tagen, Michael;
- Chang, Jae H.;
- Boyce-Rustay, Janel;
- Friesenhahn, Michel;
- Hackos, David H.;
- Hains, Avis;
- Sutherlin, Dan;
- Ward, Michael;
- Cho, William
Publication type:
Article
Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions.
Published in:
Nature Communications, 2017, v. 8, n. 3, p. 14644, doi. 10.1038/ncomms14644
By:
- Chiang, Eugene Y.;
- Li, Tianbo;
- Jeet, Surinder;
- Peng, Ivan;
- Zhang, Juan;
- Lee, Wyne P.;
- DeVoss, Jason;
- Caplazi, Patrick;
- Chen, Jun;
- Warming, Søren;
- Hackos, David H.;
- Mukund, Susmith;
- Koth, Christopher M.;
- Grogan, Jane L.
Publication type:
Article
Thermodynamic analysis of P2X7 purinoceptor ligand binding.
Published in:
FASEB Journal, 2008, v. 22, p. 627, doi. 10.1096/fasebj.22.2_supplement.627
By:
- Martin, Renee S.;
- Weber, Patrick;
- Apparsundaram, Subbu;
- Milla, Marcos E.;
- Gever, Joel R.;
- Panicker, Sandip;
- Hackos, David H.;
- Henningsen, Robert
Publication type:
Article
Cryo-EM reveals an unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.84151
By:
- Kschonsak, Marc;
- Jao, Christine C.;
- Arthur, Christopher P.;
- Rohou, Alexis L.;
- Bergeron, Philippe;
- Ortwine, Daniel F.;
- McKerrall, Steven J.;
- Hackos, David H.;
- Lunbin Deng;
- Jun Chen;
- Tianbo Li;
- Dragovich, Peter S.;
- Volgraf, Matthew;
- Wright, Matthew R.;
- Payandeh, Jian;
- Ciferri, Claudio;
- Tellis, John C.
Publication type:
Article
AF-353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist.
Published in:
2010
By:
- Gever, Joel R;
- Soto, Rothschild;
- Henningsen, Robert A;
- Martin, Renee S;
- Hackos, David H;
- Panicker, Sandip;
- Rubas, Werner;
- Oglesby, Ian B;
- Dillon, Michael P;
- Milla, Marcos E;
- Burnstock, Geoffrey;
- Ford, Anthony PDW;
- Ford, Anthony P D W
Publication type:
journal article
Toxigenic Clostridium perfringens Isolated from At-Risk Paediatric Inflammatory Bowel Disease Patients.
Published in:
Journal of Crohn's & Colitis, 2024, v. 18, n. 7, p. 985, doi. 10.1093/ecco-jcc/jjae016
By:
- Kuo, James;
- Uzunovic, Jasmina;
- Jacobson, Amanda;
- Dourado, Michelle;
- Gierke, Sarah;
- Rajendram, Manohary;
- Keilberg, Daniela;
- Mar, Jordan;
- Stekol, Emily;
- Curry, Joanna;
- Verstraete, Sofia;
- Lund, Jessica;
- Liang, Yuxin;
- Tamburini, Fiona B;
- Omattage, Natalie S;
- Masureel, Matthieu;
- Rutherford, Steven T;
- Hackos, David H;
- Tan, Man-Wah;
- Byrd, Allyson L
Publication type:
Article
Histone Deacetylase 2 Cell Autonomously Suppresses Excitatory and Enhances Inhibitory Synaptic Function in CAl Pyramidal Neurons.
Published in:
Journal of Neuroscience, 2013, v. 33, n. 14, p. 5924, doi. 10.1523/JNEUROSCI.3162-12.2013
By:
- Hanson, Jesse E.;
- Deng, Lunbin;
- Hackos, David H.;
- Shih-Ching Lo;
- Lauffer, Benjamin E.;
- Steiner, Pascal;
- Qiang Zhou
Publication type:
Article

Found: 12

Context-Specific Stress Causes Compartmentalized SARM1 Activation and Local Degeneration in Cortical Neurons.

Computationally Discovered Potentiating Role of Glycans on NMDA Receptors.

Whole genome sequencing across clinical trials identifies rare coding variants in GPR68 associated with chemotherapy-induced peripheral neuropathy.

Pannexin-1 Is Blocked by Its C-Terminus through a Delocalized Non-Specific Interaction Surface.

Correction to: Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel Na<sub>V</sub>1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers.

Safety, Tolerability, and Pharmacokinetics of GDC-0276, a Novel Na<sub>V</sub>1.7 Inhibitor, in a First-in-Human, Single- and Multiple-Dose Study in Healthy Volunteers.

Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions.

Thermodynamic analysis of P2X7 purinoceptor ligand binding.

Cryo-EM reveals an unprecedented binding site for Na<sub>V</sub>1.7 inhibitors enabling rational design of potent hybrid inhibitors.

AF-353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist.

Toxigenic Clostridium perfringens Isolated from At-Risk Paediatric Inflammatory Bowel Disease Patients.

Histone Deacetylase 2 Cell Autonomously Suppresses Excitatory and Enhances Inhibitory Synaptic Function in CAl Pyramidal Neurons.