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- Title
Imaging predictor of ophthalmic involvement in maxillary sinus cancer during super selective intra-arterial cisplatin infusion and concomitant radiotherapy (RADPLAT).
- Authors
Ashida, Hirokazu; Igarashi, Takao; Nozawa, Yosuke; Munetomo, Yohei; Higuchi, Takahiro; Yamauchi, Hideomi; Baba, Akira; Abe, Yukiko; Shimura, Eiji; Kessoku, Hisashi; Nishiya, Yukio; Kojima, Hiromi; Ojiri, Hiroya
- Abstract
Objective: To investigate the predictability of ophthalmic artery involvement in maxillary sinus cancer using preprocedural contrast enhanced CT and MRI. Methods: We analyzed advanced (T3, T4a, and T4b) primary maxillary sinus squamous cell carcinoma treated with super-selective intra-arterial cisplatin infusion and concomitant radiotherapy (RADPLAT) from Oct 2016 to Mar 2020. Two diagnostic radiologists evaluated the tumor invasion site around the maxillary sinus using preprocedural imaging. These results were compared with the angiographic involvement of the ophthalmic artery using statistical analyses. We also evaluated our RADPLAT quality using complication rate, response to treatment, local progressive free survival (LPFS), and overall survival (OS). Results: Twenty patients were included in this study. There were ten cases of ophthalmic artery tumor stain and there was a correlation between ophthalmic artery involvement and invasion for ethmoid sinus with statistically significant differences. Other imaging findings were not associated with ophthalmic artery involvement. Conclusions: Ethmoid sinus invasion on preprocedural imaging could suggest ophthalmic artery involvement in maxillary sinus cancer. It may be useful in predicting prognosis and treatment selection.
- Subjects
MAXILLARY sinus; INTRA-arterial infusions; MAXILLARY artery; OPHTHALMIC artery; FORECASTING; MAXILLARY sinus diseases
- Publication
Head & Face Medicine, 2021, Vol 17, Issue 1, p1
- ISSN
1746-160X
- Publication type
Article
- DOI
10.1186/s13005-021-00285-z