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- Title
Proton magnetic resonance spectroscopy in oncology: the fingerprints of cancer?
- Authors
García-Figueiras, Roberto; Baleato-González, Sandra; Padhani, Anwar R.; Oleaga, Laura; Vilanova, Joan C.; Luna, Antonio; Gómez, Juan Carlos Cobas; Cobas Gómez, Juan Carlos
- Abstract
Abnormal metabolism is a key tumor hallmark. Proton magnetic resonance spectroscopy (1H-MRS) allows measurement of metabolite concentration that can be utilized to characterize tumor metabolic changes. 1H-MRS measurements of specific metabolites have been implemented in the clinic. This article performs a systematic review of image acquisition and interpretation of 1H-MRS for cancer evaluation, evaluates its strengths and limitations, and correlates metabolite peaks at 1H-MRS with diagnostic and prognostic parameters of cancer in different tumor types.
- Subjects
PROTON magnetic resonance spectroscopy; ONCOLOGY; METABOLITE analysis; TUMOR markers; CHOLINE; PROGNOSIS; TUMORS
- Publication
Diagnostic & Interventional Radiology, 2016, Vol 22, Issue 1, p75
- ISSN
1305-3825
- Publication type
journal article
- DOI
10.5152/dir.2015.15009