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- Title
DGIdb: mining the druggable genome.
- Authors
Griffith, Malachi; Griffith, Obi L; Coffman, Adam C; Weible, James V; McMichael, Josh F; Spies, Nicholas C; Koval, James; Das, Indraniel; Callaway, Matthew B; Eldred, James M; Miller, Christopher A; Subramanian, Janakiraman; Govindan, Ramaswamy; Kumar, Runjun D; Bose, Ron; Ding, Li; Walker, Jason R; Larson, David E; Dooling, David J; Smith, Scott M
- Abstract
The Drug-Gene Interaction database (DGIdb) mines existing resources that generate hypotheses about how mutated genes might be targeted therapeutically or prioritized for drug development. It provides an interface for searching lists of genes against a compendium of drug-gene interactions and potentially 'druggable' genes. DGIdb can be accessed at http://dgidb.org/.
- Subjects
DATA mining; RECOMBINANT drugs; DRUG development; DATABASES; HYPOTHESIS; PHARMACOLOGY
- Publication
Nature Methods, 2013, Vol 10, Issue 12, p1209
- ISSN
1548-7091
- Publication type
Article
- DOI
10.1038/nmeth.2689