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- Title
Recent Advances in the Domino Annulation Reaction of Quinone Imines.
- Authors
Wang, Zhen-Hua; Fu, Xiao-Hui; Li, Qun; You, Yong; Yang, Lei; Zhao, Jian-Qiang; Zhang, Yan-Ping; Yuan, Wei-Cheng
- Abstract
Quinone imines are important derivatives of quinones with a wide range of applications in organic synthesis and the pharmaceutical industry. The attack of nucleophilic reagents on quinone imines tends to lead to aromatization of the quinone skeleton, resulting in both the high reactivity and the unique reactivity of quinone imines. The extreme value of quinone imines in the construction of nitrogen- or oxygen-containing heterocycles has attracted widespread attention, and remarkable advances have been reported recently. This review provides an overview of the application of quinone imines in the synthesis of cyclic compounds via the domino annulation reaction.
- Subjects
NUCLEOPHILES; CYCLIC compounds synthesis; QUINONE derivatives; IMINES; ANNULATION; QUINONE; ORGANIC synthesis
- Publication
Molecules, 2024, Vol 29, Issue 11, p2481
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules29112481