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- Title
TAG-glucose (TyG) index in childhood: an estimate of cut-off points and the relation to cardiometabolic risk in 4- to 9-year-old children.
- Authors
Brito, Alice Divina Melo de; Hermsdorff, Helen Hermana Miranda; Filgueiras, Mariana De Santis; Vieira-Ribeiro, Sarah Aparecida; Franceschini, Sylvia do Carmo Castro; Novaes, Juliana Farias de
- Abstract
<bold>Objective: </bold>To propose cut-off points for the TAG-glucose (TyG) index in Brazilian children and evaluate the link to cardiometabolic risk.<bold>Design: </bold>A cross-sectional study with children from a municipality in Minas Gerais, Brazil. Anthropometric (weight, height, waist circumference and waist:height ratio), biochemical (lipid and glucose profile) and blood pressure (BP) tests were performed. Using the receiver operating characteristic curve, cut-off points for the TyG index were proposed according to sex using homoeostasis model of assessment - insulin resistance (IR) as the reference method.<bold>Setting: </bold>Viçosa, MG, Brazil.<bold>Participants: </bold>Children aged 4-9 years (n 515).<bold>Results: </bold>The TyG index cut-off points to identify the risk of IR were 7·9 and 8·1 for boys and girls, respectively. We observed that 48·7 % of the children had an increased TyG index. The increased TyG index was associated with overweight, total body and central fat, increased BP and altered lipid profile. Children with an increased TyG index had a higher accumulation of cardiometabolic risk factors.<bold>Conclusions: </bold>According to the cut-off points proposed by the current study, children at risk of IR estimated by the TyG index presented a higher cardiometabolic risk, including isolated risk factors, as to the higher accumulation of these.
- Subjects
BRAZIL; MINAS Gerais (Brazil); RECEIVER operating characteristic curves; WAIST circumference; FAT; BRAZILIANS; TRIGLYCERIDES; RESEARCH; CROSS-sectional method; RESEARCH methodology; CARDIOVASCULAR diseases; BLOOD sugar; MEDICAL cooperation; EVALUATION research; COMPARATIVE studies; GLUCOSE; BODY mass index; INSULIN resistance
- Publication
Public Health Nutrition, 2021, Vol 24, Issue 9, p2603
- ISSN
1368-9800
- Publication type
journal article
- DOI
10.1017/S1368980020000944