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- Title
High Prevalence of Orthostatic Hypotension in Mild Dementia.
- Authors
Sonnesyn, Hogne; Nilsen, Dennis W.; Rongve, Arvid; Nore, Sabine; Ballard, Clive; Tysnes, Ole B.; Aarsland, Dag
- Abstract
Background/Aims: Orthostatic hypotension (OH) and QTc prolongation have potentially important prognostic and therapeutic consequences but have rarely been studied in patients with mild dementia. Methods: Patients with mild dementia were diagnosed according to consensus criteria after comprehensive standardized assessment. OH and QTc were assessed using standardized criteria. Results: OH was significantly more common in the dementia than in the control group, and systolic drop was higher in those with dementia with Lewy bodies. There were no significant differences in QTc values between dementia and control subjects. Conclusion: OH occurs even in patients with mild dementia, in particular in dementia with Lewy bodies. QTc was not prolonged in patients with mild dementia compared with normal controls. Copyright © 2009 S. Karger AG, Basel
- Subjects
ORTHOSTATIC hypotension; THERAPEUTICS; DEMENTIA patients; CONTROL groups; DISEASES in older people; ANTIPSYCHOTIC agents
- Publication
Dementia & Geriatric Cognitive Disorders, 2009, Vol 28, Issue 4, p307
- ISSN
1420-8008
- Publication type
Article
- DOI
10.1159/000247586