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- Title
Association of Depression with Antihypertensive Medication Adherence in Older Adults: Cross-Sectional and Longitudinal Findings from CoSMO.
- Authors
Krousel-Wood, Marie; Islam, Tareq; Muntner, Paul; Holt, Elizabeth; Joyce, Cara; Morisky, Donald E.; Webber, Larry S.; Frohlich, Edward D.
- Abstract
Background: Little is known about the associations between depressive symptoms, social support and antihypertensive medication adherence in older adults. Purpose: We evaluated the cross-sectional and longitudinal associations between depressive symptoms, social support and antihypertensive medication adherence in a large cohort of older adults. Methods: A cohort of 2,180 older adults with hypertension was administered questionnaires, which included the Center for Epidemiologic Studies-Depression Scale, the Medical Outcomes Study Social Support Index, and the hypertension-specific Morisky Medication Adherence Scale at baseline and 1 year later. Results: Overall, 14.1% of participants had low medication adherence, 13.0% had depressive symptoms, and 33.9% had low social support. After multivariable adjustment, the odds ratios that participants with depressive symptoms and low social support would have low medication adherence were 1.96 (95% confidence interval (CI) 1.43, 2.70) and 1.27 (95% CI 0.98, 1.65), respectively, at baseline and 1.87 (95% CI 1.32, 2.66) and 1.30 (95% CI 0.98, 1.72), respectively, at 1 year follow-up. Conclusion: Depressive symptoms may be an important modifiable barrier to antihypertensive medication adherence in older adults
- Subjects
ANTIHYPERTENSIVE agents; PATIENT compliance; CROSS-sectional method; LONGITUDINAL method; SOCIAL support; HYPERTENSION in old age; CENTER for Epidemiologic Studies Depression Scale
- Publication
Annals of Behavioral Medicine, 2010, Vol 40, Issue 3, p248
- ISSN
0883-6612
- Publication type
Article
- DOI
10.1007/s12160-010-9217-1