A response by Simon Storgård Jensen, Nina Broggini, Gernot Weibrich, Erik Hjôrting-Hansen, Robert Schenk and Daniel Buser to a letter to the editor about their article “Bone Regeneration in Standardized Bone Defects with Autografts or Bone Substitutes in Combination with Platelet Concentrate: A Histologic and Histomorphometric Study in the Mandibles of Minipigs,” in a 2005 issue is presented.