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- Title
Ketoprofen hypersensibility - a case report and literature review.
- Authors
Korzeniowska, Katarzyna; Malesza, Katarzyna
- Abstract
Background. Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), is a potent inhibitor of cyclooxygenase that inhibits the synthesis of prostaglandins. It is widely used as an analgesic, anti-inflammatory, and antipyretic drug. However, there have been reports of a steady increase of allergic reactions to this medication. Material and methods. We describe a case report of a 27-year-old patient who experienced adverse reactions of dyspnea and skin lesions a few minutes after intravenously administered ketoprofen due to pain after FESS (Functional Endoscopic Sinus Surgery). Results. The patient was administered dexamethasone and hydroxyzine, which resulted in clinical improvement. Instead of ketoprofen, the patient was treated with paracetamol (i.v.) in a dose of up to 2 g/day without complications. Conclusions. The described case confirms the risk of allergic reaction following the administration of ketoprofen. This adverse effect is especially dangerous for patients with concomitant respiratory diseases (e.g. asthma), therefore the administration of NSAIDs should be avoided in these patients, and paracetamol should be preferred.
- Subjects
DRUG side effects; NONSTEROIDAL anti-inflammatory agents; LITERATURE reviews; ANTI-inflammatory agents; ALLERGIES
- Publication
Anaesthesiology & Rescue Medicine / Anestezjologia i Ratownictwo, 2022, Vol 16, Issue 2, p67
- ISSN
1898-0732
- Publication type
Case Study
- DOI
10.53139/AIR.20221610