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- Title
Good outcome of kidney transplants in recipients of young donors: a NAPRTCS data analysis.
- Authors
Moudgil, Asha; Martz, Karen; Stablein, Donald M.; Puliyanda, Dechu P.
- Abstract
Moudgil A, Martz K, Stablein DM, Puliyanda DP. Good outcome of kidney transplants in recipients of young donors: a NAPRTCS data analysis. Pediatr Transplantation 2011: 15:167-171. © 2010 John Wiley & Sons A/S. NAPRTCS data were analyzed to assess outcome of TX recipients from YDs (<5 yr) in comparison with IDs (6-35 yr) and ODs (36-55 yr). Of 9854 TX in NAPRTCS (1987-2003), 469 were YD. Patient survival (PS) and graft survival (GS) were compared between DD TX after 1995; 81YD, 1324 ID, and 429 OD and eGFR were compared among functioning grafts (YD 31, ID 439, OD 174) at three yr. PS was comparable in all groups; GS at one, two, and three yr in TX of YD (91.1%, 83.8%, 79.7%), ID (93.5%, 89.7%, 83.6%), and OD (92.2%, 87.2%, 82.4%) was comparable. The eGFR in YD was comparable to ID but better than OD (86.5 vs. 79.7 vs. 67.2 mL/min/1.73 m, p 0.139 and <0.0003). Primary graft non-function was more frequent in TX from YD than ID and OD (3.7% vs. 0.3 and 0.7%, p = 0.004); the incidence of vascular thrombosis was similar. The aforementioned data show that pediatric recipients of YD had equivalent patient and graft survival. Although primary graft non-function was higher, eGFR of functioning grafts was comparable to ID. With further improvements in care, kidneys from YD may present a viable option for transplantation.
- Subjects
PEDIATRIC diagnosis; KIDNEY transplant patients; ORGAN donors; THROMBOSIS; HEMODIALYSIS equipment
- Publication
Pediatric Transplantation, 2011, Vol 15, Issue 2, p167
- ISSN
1397-3142
- Publication type
Article
- DOI
10.1111/j.1399-3046.2010.01432.x