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- Title
Bronchiolitis Due to RSV and HMPV—Epidemiology, Clinical Course, and Prognosis: Experience of a Single Tertiary Center.
- Authors
Azar, Bar; Hashavya, Saar; Ohana Sarna Cahan, Lea; Reif, Shimon; Gross, Itai
- Abstract
Acute bronchiolitis is a leading cause of hospitalization in infants. In this retrospective study, 645 patients with acute bronchiolitis diagnosed as respiratory syncytial virus (RSV; n = 538) or human metapneumovirus (HMPV; n = 107) were compared in terms of demographic, clinical, and laboratory findings. The HMPV patients presented later in the winter, were older (20 vs 7.55 months; P <.001)), had higher levels of C-reactive protein (4.55 vs 3.03 mg/dL; P =.007), and a higher prevalence of complications (43.9% vs 32.7%; P =.03). This study highlights the similarities and differences between these 2 common respiratory viral pathogens and shows that HMPV has a slightly more severe disease course than RSV. These findings can help guide approaches to these 2 common viruses that cause bronchiolitis.
- Subjects
ISRAEL; METABOLISM in RNA viruses; RESPIRATORY syncytial virus; C-reactive protein; INTENSIVE care units; LENGTH of stay in hospitals; ACADEMIC medical centers; ASTHMA; CHEST X rays; ALBUTEROL; ADRENALINE; AGE distribution; HOSPITAL care of newborn infants; PEDIATRICS; TERTIARY care; ACQUISITION of data; FISHER exact test; IMMUNOSUPPRESSION; RETROSPECTIVE studies; PATIENTS; BRONCHITIS; SEVERITY of illness index; TREATMENT effectiveness; COMPARATIVE studies; HOSPITAL admission &; discharge; SEASONS; MEDICAL records; CHI-squared test; DESCRIPTIVE statistics; CYANOSIS; OXYGEN therapy; ELECTRONIC health records; DATA analysis software; HYPERTONIC saline solutions; DISEASE complications; CHILDREN
- Publication
Clinical Pediatrics, 2023, Vol 62, Issue 9, p1032
- ISSN
0009-9228
- Publication type
Article
- DOI
10.1177/00099228231151401