We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Radiation-Induced Colo-rectal Carcinoma — A Report of Seven Cases —.
- Authors
MORIYA, YOSHIHIRO; KOYAMA, YASUO; HOJO, KEIICHI; USHIO, KYOSUKE; HIROTA, TERUYUKI; ITABASHI, MASAYUKI
- Abstract
Seven cases of colo-rectal carcinoma which were considered to have developed secondarily to radiation injuries are reported. The incidence in our series was 0.8% (seven out of 880 primary colo-rectal carcinomas). Initial diseases, the targets of radiotherapy, were five carcinomas of the uterine cervix, one of the cecum, and one of the vulva.The latent period, the interval between the initiation of irradiation and the detection of colo-rectal carcinoma, varied from 16 to 21 years with an average of 18 years.Late radiation injuries were confirmed histologically in the segments of the resected bowel involved in all cases. Postoperative complications were highly related to the radiation injuries of the urinary bladder, macrohematuria in two and vesical fistula in three.Among the seven patients, four died within five years and three months, two of postoperative complications and two of recurrence of the disease; the other three are alive and well without evidence of disease, for three years and seven months, three years and three months, and 11 months, respectively.
- Publication
Japanese Journal of Clinical Oncology, 1979, Vol 9, Issue 1, p153
- ISSN
0368-2811
- Publication type
Article