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- Title
Unveiling the Mysteries of RAS Signaling: A Journey of Discovery and Breakthroughs.
- Authors
Castellano, Esther
- Abstract
This document, titled "Unveiling the Mysteries of RAS Signaling: A Journey of Discovery and Breakthroughs," celebrates the advancements made in understanding RAS signaling in health and disease. It includes a collection of review articles that delve into various aspects of RAS signaling, such as its interactions on the cellular membrane, the significance of RAS dimers, the crosstalk between RAS and PI3K, and the targeting of RAS in cancer treatment. The document also explores the interplay between RAS and RHO signaling pathways, the involvement of Ras GTPases in kidney fibrosis, and the role of wild-type RAS in oncogenic RAS transformation. It concludes by acknowledging the efforts of scientists, researchers, and clinicians in decoding the complexities of RAS signaling and envisioning future possibilities.
- Subjects
RAS proteins; RENAL fibrosis; RESEARCH personnel; CELLULAR signal transduction; PHOSPHATIDYLINOSITOL 3-kinases
- Publication
Genes, 2023, Vol 14, Issue 11, p1987
- ISSN
2073-4425
- Publication type
Article
- DOI
10.3390/genes14111987