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- Title
Are We Ready to Recommend Capsaicin for Disorders Other Than Neuropathic Pain?
- Authors
Silva, Janayne L.; Santos, Elandia A.; Alvarez-Leite, Jacqueline I.
- Abstract
Capsaicin, a lipophilic, volatile compound, is responsible for the pungent properties of chili peppers. In recent years, a significant increase in investigations into its properties has allowed the production of new formulations and the development of tools with biotechnological, diagnostic, and potential therapeutic applications. Most of these studies show beneficial effects, improving antioxidant and anti-inflammatory status, inducing thermogenesis, and reducing white adipose tissue. Other mechanisms, including reducing food intake and improving intestinal dysbiosis, are also described. In this way, the possible clinical application of such compound is expanding every year. This opinion article aims to provide a synthesis of recent findings regarding the mechanisms by which capsaicin participates in the control of non-communicable diseases such as obesity, diabetes, and dyslipidemia.
- Subjects
DIET therapy for diabetes; THERAPEUTIC use of capsaicin; REDUCING diets; NON-communicable diseases; NEURALGIA; ANTI-inflammatory agents; GUT microbiome; INFLAMMATION; ANTIOXIDANTS; BODY temperature regulation; CAPSAICIN; ADIPOSE tissues; PHARMACODYNAMICS
- Publication
Nutrients, 2023, Vol 15, Issue 20, p4469
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu15204469