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- Title
Is bipolar disorder a risk for cigarette smoking in ADHD youth?
- Authors
Wilens, Timothy E.; Biederman, Joseph; Milberger, Sharon; Hahesy, Amy L.; Goldman, Sarah; Wozniak, Janet; Spencer, Thomas J.; Wilens, T E; Biederman, J; Milberger, S; Hahesy, A L; Goldman, S; Wozniak, J; Spencer, T J
- Abstract
Despite emerging literature linking juvenile bipolar disorder (BPD) and substance abuse, little is known about a link between BPD and cigarette smoking. To this end, we evaluated the association between BPD and cigarette smoking in youth. Subjects were 31 bipolar adolescents derived from a cohort of boys with DSM-III-R ADHD (N = 128) and non-ADHD comparisons (N = 109) followed prospectively for 4 years into mid-adolescence. Information on cigarette smoking was obtained in a standardized manner blind to the proband's clinical status. Logistic regression models were used to determine risk for smoking at follow-up. BPD was associated with a higher risk for cigarette smoking in mid-adolescence, which was largely accounted for by conduct disorder. The developmental onset of BPD in adolescence (age 13-18 years) conferred a greater risk for cigarette smoking compared to those youths with the onset of their BPD prepubertally (< or = 12 years; odds ratio = 10.8, p < 0.01), even after controlling for conduct disorder and other confounds. The naturalistic treatment of BPD with combined counseling and pharmacotherapy appeared to reduce the risk for cigarette smoking. BPD, particularly when it onsets in adolescence, is a significant risk factor for the early initiation of cigarette smoking in these ADHD youths. These data coupled with the literature strongly suggest that juveniles with BPD need to be carefully monitored for the early initiation of cigarette smoking and substance abuse.
- Subjects
UNITED States; BIPOLAR disorder; CIGARETTE smokers; SMOKING; SMOKING &; psychology; ATTENTION-deficit hyperactivity disorder; ADOLESCENT psychopathology; LOGISTIC regression analysis; HEALTH; DRUG therapy; MENTAL illness risk factors; COMPARATIVE studies; LONGITUDINAL method; RESEARCH methodology; MEDICAL cooperation; RESEARCH; RESEARCH funding; TEENAGERS' conduct of life; EVALUATION research; DISEASE complications; PSYCHOLOGY
- Publication
American Journal on Addictions, 2000, Vol 9, Issue 3, p187
- ISSN
1055-0496
- Publication type
journal article
- DOI
10.1080/10550490050148017