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- Title
Intrapartum Azithromycin vs Placebo for Neonatal Sepsis.
- Authors
Gu, Wan-Jie; Lyu, Jun; Yin, Hai-Yan
- Abstract
Comment & Response B To the Editor b We have several comments about the recent randomized clinical trial[1] that investigated the effect of intrapartum azithromycin on neonatal sepsis and death. Effect of intrapartum azithromycin vs placebo on neonatal sepsis and death: a randomized clinical trial. First, some preexisting medical comorbidities, such as diabetes and hypertension, are very common during pregnancy and are associated with an increased risk of neonatal sepsis and mortality.[2] In addition, premature rupture of membranes is a risk factor for neonatal sepsis and mortality.[2] However, the PregnAnZI-2 trial did not provide data about the above risk factors.
- Subjects
NEONATAL sepsis; AZITHROMYCIN; PLACEBOS; NEONATAL infections
- Publication
JAMA: Journal of the American Medical Association, 2023, Vol 330, Issue 2, p187
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.2023.8328