We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Cytotoxic constituents of Saussurea lappa.
- Authors
Jung, Jee; Kim, Youngsoo; Lee, Chong-Ock; Kang, Sam; Park, Jong-Hee; Im, Kwang
- Abstract
The crude extract of Saussurea lappa displayed significant lethality to brine shrimp larvae. Investigation of the causative components by bioactivity-directed fractionation resulted in the isolation of three C17-polyene alcohols. Based on various nmr spectral data, these compounds were idenfitied as shikokiols which had been previously isolated from Cirsium nipponicum and/or Centaurea aegyptica. These C17-polyene alcohols exhibited moderate cytotoxicities against the human tumor cell lines, A549, SK-OV-3, SK-MEL-2, XF498, and HCT15.
- Publication
Archives of Pharmacal Research, 1998, Vol 21, Issue 2, p153
- ISSN
0253-6269
- Publication type
Article
- DOI
10.1007/BF02974020