We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Evaluation of the Role of Oropharyngeal Fatty Infiltration In Obstructive Sleep Apnea Syndrome.
- Authors
Abdel-Rahman, Ahmed H.; Salem, Ahmed S.; Gad, Ahmed S.; Nassar, Ahmed Moh.; Abdalla, Aly; Abdel-Baset, Ahmed; Abdel-Kawy, Mohammed; Khodeir, Mostafa M.; Abdel-Hamid, Hanan S.
- Abstract
Background: Obstructive sleep apnea (OSA) patients owing to oropharyngeal fatty infiltration have a narrower pharyngeal airway than the normal individuals. Material and Methods: To identify potential fatty infiltration of the pharyngeal tissues that may contribute to OSA syndrome, a histologic study of the distal soft palate was performed on a sum of 100 cases including OSA patients (80 cases) and normal subjects (20 cases) taken as controls. All cases were divided according the body mass index (BMI) into two OSA groups (group 1: normal weight OSA; 25 cases & group 2: overweight OSA; 55 cases) and two control non-OSA groups (group 3: normal weight controls; 10 cases & group 4: overweight controls; 10 cases). All specimens underwent a quantitative analysis of the fatty tissue that showed an excessive fatty infiltration in all oropharyngeal biopsies received from OSA groups compared to a normal infiltration in conrol biopsies. Results: No significant correlation was found between the pharyngeal fatty infiltration on one side and BMI or apnea index (AI) on the other . Absence of an excessive fatty infiltration in the control subjects, irrespective to his or her weight, and its presence in all studied OSA patients concluded that this event may play a role in the upper airway obstruction and can be associated with the development of apnea.
- Subjects
SLEEP apnea syndromes; AIRWAY (Company); BODY mass index; BIOPSY; RESPIRATORY obstructions; APNEA; PATIENTS
- Publication
Egyptian Journal of Hospital Medicine, 2008, Vol 32, p417
- ISSN
1687-2002
- Publication type
Article