We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Alkaloids from Ochrosia borbonica.
- Authors
Zhang, Bing-Jie; Yan, Ju-Ming; Wu, Zi-Kun; Liu, Ya-Ping; Bao, Mei-Fen; Cheng, Gui-Guang; Luo, Xiao-Dong; Cai, Xiang-Hai; Li, Yan
- Abstract
Ten new monoterpenoid indole alkaloids, ochroborines A and B ( 1 and 2, resp.), 10-hydroxyisovallesiachotamine ( 3), 10-hydroxyisositsirikine ( 4), 10,11-dimethoxysitsirikine ( 5), 10-methoxyapoyohimbine ( 6), 10-hydroxyakuammidine ( 7), akuammidine 17- O- β- D-glucoside ( 8), 15 α-hydroxyapparicine ( 9), and 15 α-hydroxy-10-methoxyapparicine ( 10), and 24 known alkaloids were isolated from leaves and twigs of Ochrosia borbonica J. F. Gmel. These structures were elucidated based on 1D- and 2D-NMR, FT-IR, UV, and MS data. 10-Hydroxyisovallesiachotamine ( 3), ellipticine, and 10-methoxyellipticine showed cytotoxic activities against five human cancer cell lines.
- Subjects
ALKALOIDS; MICROBIAL metabolites; APOCYNACEAE; GENTIANALES; MONOTERPENOIDS
- Publication
Helvetica Chimica Acta, 2013, Vol 96, Issue 12, p2288
- ISSN
0018-019X
- Publication type
Article
- DOI
10.1002/hlca.201300136