We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Synthesis and Crystal Structures of Two 92BromoethylSubstituted 7Deazapurines.
- Authors
Simona Asaftei; Martin Reichelt; Hans Reuter; Helmut Rosemeyer
- Abstract
The 72bromoethyl derivatives, 2aand 2b, of 4chloro7Hpyrrolo2,3dpyrimidine 1a and 4chloro7Hpyrrolo2,3dpyrimidin2amine 1b were synthesized by nucleobase anion alkylation NaH, DMF and crystallized. XRay analyses of both compounds were performed, and they revealed significantly different positioning of the side chain relative to the heterocyclic ring, depending on the substituent H or NH2 at C2.
- Subjects
PURINE synthesis; CHEMICAL structure; SUBSTITUTION reactions; ETHYLENE dibromide; ALKYLATION; HETEROCYCLIC compounds
- Publication
Helvetica Chimica Acta, 2009, Vol 92, Issue 10, p1944
- ISSN
0018-019X
- Publication type
Article
- DOI
10.1002/hlca.200900145