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- Title
Transcriptional profile of Marek's disease virus genes in chicken thymus during different phases of MDV infection.
- Authors
Hu, Xuming; Qin, Aijian; Miao, Ji; Xu, Wencai; Yu, Chuan; Qian, Kun; Shao, Hongxia
- Abstract
In this study, 86 Marek's disease virus (MDV) transcripts were detected in chicken thymus infected with RB1B strain. Forty-seven of them, which were mainly involved in viral replication and immune escape, were detected at 7 days postinfection (dpi). Expression of most of the genes was increased at 21 and 28 dpi but reduced or shut down at 14 dpi. Unlike others tissues, we found that a latent infection was established at 14 dpi in infected thymus. Here, we show the kinetics of expression of MDV transcripts and their relative expression in infected thymus.
- Subjects
MAREK'S disease virus; VIRAL genes; CHICKEN diseases; THYMUS diseases; VIRAL replication; GENE expression in viruses; VETERINARY virology
- Publication
Archives of Virology, 2013, Vol 158, Issue 8, p1787
- ISSN
0304-8608
- Publication type
Report
- DOI
10.1007/s00705-013-1665-z