We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
CausalR: extracting mechanistic sense from genome scale data.
- Authors
Bradley, Glyn; Barrett, Steven J.
- Abstract
Summary: Utilization of causal interaction data enables mechanistic rather than descriptive interpretation of genome-scale data. Here we present CausalR, the first open source causal network analysis platform. Implemented functions enable regulator prediction and network reconstruction, with network and annotation files created for visualization in Cytoscape. False positives are limited using the introduced Sequential Causal Analysis of Networks approach.
- Subjects
GENOMICS; MOLECULAR biology; PROTEIN-protein interactions; MACHINE learning; BIOINFORMATICS
- Publication
Bioinformatics, 2017, Vol 33, Issue 22, p3670
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btx425