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- Title
Cordova: Web-based management of genetic variation data.
- Authors
Ephraim, Sean S.; Anand, Nikhil; DeLuca, Adam P.; Taylor, Kyle R.; Kolbe, Diana L.; Simpson, Allen C.; Azaiez, Hela; Sloan, Christina M.; Shearer, A. Eliot; Hallier, Andrea R.; Casavant, Thomas L.; Scheetz, Todd E.; Smith, Richard J. H.; Braun, Terry A.
- Abstract
Summary: Cordova is an out-of-the-box solution for building and maintaining an online database of genetic variations integrated with pathogenicity prediction results from popular algorithms. Our primary motivation for developing this system is to aid researchers and clinician–scientists in determining the clinical significance of genetic variations. To achieve this goal, Cordova provides an interface to review and manually or computationally curate genetic variation data as well as share it for clinical diagnostics and the advancement of research.Availability and implementation: Cordova is open source under the MIT license and is freely available for download at https://github.com/clcg/cordova. Contact: sean.ephraim@gmail.com or terry-braun@uiowa.edu
- Subjects
ONLINE databases; COMPUTER interfaces; COMPUTER algorithms; ONLINE information services; HUMAN genetic variation
- Publication
Bioinformatics, 2014, Vol 30, Issue 23, p3438
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btu539