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- Title
Vascular Distensibility as a Predictive Tool in the Management of Small Asymptomatic Abdominal Aortic Aneurysms.
- Authors
Hoegh, Annette; Lindholt, Jes S.
- Abstract
Background: This study investigates whether baseline aortic wall distensibility serves as a supplemental biomarker for AAA progression and need for later repair. Methods: In 1998, 61 males with a small asymptomatic AAAs had a baseline measurement of elasticity and stiffness, using an echo-tracking ultrasound system (Diamove). The cohort was followed till 2005 concerning Dmax, expansion rate, operations for AAA, hospitalisation do to cardiovascular disease and death. Results: During follow-up, 49% died, and 45.9% were hospitalised do to cardiovascular disease, compared to Dmax, Ep and β no significant associations were found. Elasticity correlated moderately to annual expansion rate and Dmax. Good correlation was found between annual expansion rate and Dmax. ROC-curve analysis showed that elasticity, stiffness and Dmax all tended to predict future need for AAA-repair. Conclusion: Baseline aortic wall distensibility may provide an additional parameter for AAA to optimize the indication and time for elective repair.
- Subjects
AORTIC aneurysms; BIOMARKERS; CARDIOVASCULAR diseases; HOSPITAL care; COHORT analysis
- Publication
Vascular & Endovascular Surgery, 2009, Vol 43, Issue 4, p333
- ISSN
1538-5744
- Publication type
Article
- DOI
10.1177/1538574409336019