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- Title
Clinical evaluation of periodontal pathogen levels by real-time polymerase chain reaction in peri-implantitis patients.
- Authors
Ito, Taichi; Mori, Gentaro; Oda, Yukari; Hirano, Tomoki; Sasaki, Hodaka; Honma, Shinya; Furuya, Yoshitaka; Yajima, Yasutomo
- Abstract
Objective: The mechanisms underlying the onset and progression of peri-implantitis are similar to those of periodontitis, and the causative bacteria are believed to similar. Previous studies support an association between peri-implantitis and periodontal pathogen. Thus, we investigated the bacterial flora of peri-implantitis patients in comparison to those of healthy implant and periodontitis patients. Materials and methods: In total, 70 patients visiting Tokyo Dental College Chiba Hospital were divided into four groups: healthy, periodontitis, healthy implant, and peri-implantitis. For each group, the following five periodontal pathogens were detected using real-time polymerase chain reaction: Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Tannerella forsythia, Treponema denticola, and Prevotella intermedia. Results: The average copy number of total bacteria was significantly higher in the periodontitis group than in the other groups. P. gingivalis was detected in the periodontitis and peri-implantitis groups at levels as high as 18.92% and 12.29%, respectively, and P. intermedia was found in the peri-implantitis group at a rate of 2.06%. Nevertheless, periodontal pathogens were generally detected at lower levels in the peri-implantitis group than in the periodontitis group. Conclusion: We found lower bacterial counts in the peri-implantitis group relative to the periodontitis group. Our results suggest that the peri-implant tissue is less resistant to bacteria, so even a small number of bacteria can be a risk factor for peri-implantitis and the causative agent of peri-implantitis can be bacteria other than periodontal pathogen.
- Subjects
POLYMERASE chain reaction; PERI-implantitis; ACTINOBACILLUS actinomycetemcomitans; PORPHYROMONAS gingivalis; DENTAL schools
- Publication
International Journal of Implant Dentistry, 2021, Vol 7, Issue 1, p1
- ISSN
2198-4034
- Publication type
Article
- DOI
10.1186/s40729-021-00385-0