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- Title
Channelling protons out of the heart.
- Authors
Swietach, Pawel; Despa, Sanda
- Abstract
The HVCN1 voltage-gated proton channel contributes to pH regulation in canine ventricular myocytes. Keywords: acid-base balance; cardiomyocyte; mitochondria; voltage-gated channel EN acid-base balance cardiomyocyte mitochondria voltage-gated channel 2551 2552 2 06/03/22 20220601 NES 220601 Acid-base carriers were among the first membrane transport processes to be investigated in the 1970s. The other major metabolic source of acid is mitochondrial CO SB 2 sb production, which the authors postulate supplies the H SP + sp ions that are ultimately extruded by HVCN1 channels.
- Subjects
PROTONS; AVOGADRO'S law; HEART; BIOLOGICAL transport
- Publication
Journal of Physiology, 2022, Vol 600, Issue 11, p2551
- ISSN
0022-3751
- Publication type
Article
- DOI
10.1113/JP283250