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- Title
Author Correction: YB1 modulates the DNA damage response in medulloblastoma.
- Authors
McSwain, Leon F.; Pillsbury, Claire E.; Haji‑Seyed‑Javadi, Ramona; Rath, Sandip Kumar; Chen, Victor; Huang, Tiffany; Shahab, Shubin W.; Kunhiraman, Haritha; Ross, James; Price, Gabrielle A.; Dey, Abhinav; Hambardzumyan, Dolores; MacDonald, Tobey; Yu, David S.; Porter, Christopher C.; Kenney, Anna M.
- Abstract
( B E b ) shSCR and shYB1 non-treated and treated with 10 Gy were stained with LaminA/C and DAPI 48 h after 10 Gy irradiation. shSCR cells demonstrate more aberrations in nuclear morphology (UW228 and additional images Supp Fig. ( B C b ) -Gal stain of UW228 cells following radiation time course demonstrating increased senescence of YB1 depleted cells compared to irradiated control (5 Gy shSCR vs. 5 Gy shYB1 95% CI - 16.75-(- 5.09) I p i < 0.0001 two-way ANOVA, n = 3). ( B A3 b ) -Gal stain of ONS-76 cells following radiation time course demonstrating increased senescence of YB1 depleted cells compared to irradiated control (5 Gy shSCR vs. 5 Gy shYB1 95% CI - 22.64-(- 7.91) I p i < 0.0001 two-way ANOVA, n = 3).
- Subjects
DNA repair; MEDULLOBLASTOMA
- Publication
Scientific Reports, 2023, Vol 13, Issue 1, p1
- ISSN
2045-2322
- Publication type
Article
- DOI
10.1038/s41598-023-36594-3