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Front Cover: A Quantitative Method to Distinguish Cytosolic from Endosome‐Trapped Cell‐Penetrating Peptides (ChemBioChem 14/2024).
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- ChemBioChem, 2024, v. 25, n. 14, p. 1, doi. 10.1002/cbic.202481401
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A Quantitative Method to Distinguish Cytosolic from Endosome‐Trapped Cell‐Penetrating Peptides.
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- ChemBioChem, 2024, v. 25, n. 14, p. 1, doi. 10.1002/cbic.202400198
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- Article
Exploiting Benzophenone Photoreactivity To Probe the Phospholipid Environment and Insertion Depth of the Cell-Penetrating Peptide Penetratin in Model Membranes.
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- Angewandte Chemie, 2017, v. 129, n. 28, p. 8338, doi. 10.1002/ange.201703465
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A cationic motif upstream Engrailed2 homeodomain controls cell internalization through selective interaction with heparan sulfates.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37757-6
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Cell-Penetrating Dabcyl-Containing Tetraarginines with Backbone Aromatics as Uptake Enhancers.
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- Pharmaceutics, 2023, v. 15, n. 1, p. 141, doi. 10.3390/pharmaceutics15010141
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- Article
Exploiting Benzophenone Photoreactivity To Probe the Phospholipid Environment and Insertion Depth of the Cell-Penetrating Peptide Penetratin in Model Membranes.
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- Angewandte Chemie International Edition, 2017, v. 56, n. 28, p. 8226, doi. 10.1002/anie.201703465
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Photocontrol of the Translocation of Molecules, Peptides, and Quantum Dots through Cell and Lipid Membranes Doped with Azobenzene Copolymers.
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- Angewandte Chemie, 2012, v. 124, n. 9, p. 2174, doi. 10.1002/ange.201106777
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Quantitative fluorescence spectroscopy and flow cytometry analyses of cell-penetrating peptides internalization pathways: optimization, pitfalls, comparison with mass spectrometry quantification.
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- Scientific Reports, 2016, p. 36938, doi. 10.1038/srep36938
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Relationships between Membrane Binding, Affinity and Cell Internalization Efficacy of a Cell-Penetrating Peptide: Penetratin as a Case Study.
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- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024096
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Tryptophan, an Amino-Acid Endowed with Unique Properties and Its Many Roles in Membrane Proteins.
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- Crystals (2073-4352), 2021, v. 11, n. 9, p. 1032, doi. 10.3390/cryst11091032
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The interaction of cell-penetrating peptides with lipid model systems and subsequent lipid reorganization: thermodynamic and structural characterization.
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- Journal of Peptide Science, 2009, v. 15, n. 3, p. 200, doi. 10.1002/psc.1070
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Topographic analysis of the S<sub>7</sub> binding subsite of the tachykinin neurokinin-1 receptor.
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- Biopolymers, 1996, v. 39, n. 2, p. 133, doi. 10.1002/(SICI)1097-0282(199608)39:2<133::AID-BIP2>3.0.CO;2-Q
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Influence of the Dabcyl group on the cellular uptake of cationic peptides: short oligoarginines as efficient cell-penetrating peptides.
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- Amino Acids, 2021, v. 53, n. 7, p. 1033, doi. 10.1007/s00726-021-03003-w
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Massive glycosaminoglycan-dependent entry of Trp-containing cell-penetrating peptides induced by exogenous sphingomyelinase or cholesterol depletion.
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- Cellular & Molecular Life Sciences, 2015, v. 72, n. 4, p. 809, doi. 10.1007/s00018-014-1696-y
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ECL1i, d(LGTFLKC), a novel, small peptide that specifically inhibits CCL2-dependent migration.
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- FASEB Journal, 2016, v. 30, n. 6, p. 2370, doi. 10.1096/fj.201500116
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Tryptophan within basic peptide sequences triggers glycosaminoglycan-dependent endocytosis.
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- FASEB Journal, 2013, v. 27, n. 2, p. 738, doi. 10.1096/fj.12-216176
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Cell-surface thiols affect cell entry of disulfide-conjugated peptides.
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- FASEB Journal, 2009, v. 23, n. 9, p. 2956, doi. 10.1096/fj.08-127563
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HIV gp41 Engages gC1qR on CD4+ T Cells to Induce the Expression of an NK Ligand through the PIP3/H2O2 Pathway.
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- PLoS Pathogens, 2010, v. 6, n. 7, p. 1, doi. 10.1371/journal.ppat.1000975
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Quantification of the Cellular Uptake of Cell-Penetrating Peptides by MALDI-TOF Mass SpectrometryWe thank Dr. Alain Prochiantz and Dr. Alain Joliot for fruitful discussions. We are also grateful to Dr. John Offer and Dr. Florian Toepert for their critical comments on the manuscript.
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- Angewandte Chemie, 2005, v. 117, n. 27, p. 4316, doi. 10.1002/ange.200500477
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Anandamide and WIN 55212-2 inhibit cyclic AMP formation through G-protein-coupled receptors distinct from CB1 cannabinoid receptors in cultured astrocytes.
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- European Journal of Neuroscience, 1999, v. 11, n. 2, p. 691, doi. 10.1046/j.1460-9568.1999.00480.x
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Tryptophan, more than just an interfacial amino acid in the membrane activity of cationic cell-penetrating and antimicrobial peptides.
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- Quarterly Reviews of Biophysics, 2022, v. 55, p. 1, doi. 10.1017/S0033583522000105
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Modification of Short Non‐Permeable Peptides to Increase Cellular Uptake and Cytostatic Activity of Their Conjugates.
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- ChemistrySelect, 2021, v. 6, n. 38, p. 10111, doi. 10.1002/slct.202103150
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Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology.
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- Cells (2073-4409), 2020, v. 9, n. 2, p. 447, doi. 10.3390/cells9020447
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Quantification of the Cellular Uptake of Cell-Penetrating Peptides by MALDI-TOF Mass SpectrometryWe thank Dr. Alain Prochiantz and Dr. Alain Joliot for fruitful discussions. We are also grateful to Dr. John Offer and Dr. Florian Toepert for their critical comments on the manuscript.
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- Angewandte Chemie International Edition, 2005, v. 44, n. 27, p. 4244, doi. 10.1002/anie.200500477
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Cell-penetrating peptides: 20years later, where do we stand?
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- FEBS Letters, 2013, v. 587, n. 12, p. 1693, doi. 10.1016/j.febslet.2013.04.031
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A direct label-free MALDI-TOF mass spectrometry based assay for the characterization of inhibitors of protein lysine methyltransferases.
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- Analytical & Bioanalytical Chemistry, 2017, v. 409, n. 15, p. 3767, doi. 10.1007/s00216-017-0319-5
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Small AntiMicrobial Peptide with In Vivo Activity Against Sepsis.
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- Molecules, 2019, v. 24, n. 9, p. 1702, doi. 10.3390/molecules24091702
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Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin.
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- PLoS ONE, 2018, v. 13, n. 10, p. 1, doi. 10.1371/journal.pone.0205727
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Peptide-Grafted Nanodiamonds: Preparation, Cytotoxicity and Uptake in Cells.
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- ChemBioChem, 2008, v. 9, n. 13, p. 2113, doi. 10.1002/cbic.200800247
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Antimicrobial activity of lysozyme isoforms: Key molecular features.
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- Biopolymers, 2017, v. 107, n. 12, p. n/a, doi. 10.1002/bip.23040
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Photocontrol of the Translocation of Molecules, Peptides, and Quantum Dots through Cell and Lipid Membranes Doped with Azobenzene Copolymers.
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- Angewandte Chemie International Edition, 2012, v. 51, n. 9, p. 2132, doi. 10.1002/anie.201106777
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- Article