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- Title
Therapeutic targeting of casein kinase 1δ in breast cancer.
- Authors
Rosenberg, Laura H.; Lafitte, Marie; Quereda, Victor; Grant, Wayne; Weimin Chen; Bibian, Mathieu; Noguchi, Yoshihiko; Fallahi, Mohammad; Chunying Yang; Chang, Jenny C.; Roush, William R.; Cleveland, John L.; Duckett, Derek R.
- Abstract
The article presents a study highlights therapeutic targeting of casein kinase 1δ in breast cancer. Topics discussed include use of targeted therapeutics in identification of specific drivers of human cancer; amplified and/or overexpressed CSNK1D protein in human breast tumors; and vulnerability of human breast cancer subtypes overexpressing the casein kinase 1δ.
- Subjects
BREAST cancer diagnosis; CASEIN kinase regulation; CASEIN kinase genetics; GENETICS of breast cancer; TUMOR growth
- Publication
Science Translational Medicine, 2015, Vol 7, Issue 318, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aac8773