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- Title
Effects of regular exercise plus food restriction on left ventricular pathological remodeling in heart failure-induced rats.
- Authors
Moradi, F.; Imani, A. R.; Faghihi, M.
- Abstract
OBJECTIVE: This study investigated the association between serum uric acid (sUA) and stroke risk in men with hypertriglyceridemia. METHODS: Between 2002 and 2012, male patients with pure hypertriglyceridemia and a triglyceride (TG) level 150 mg/dL were enrolled. Eligible patients were categorized into two groups according to their sUA levels ( and < 8 mg/dL). Clinical characteristics and comorbidities that are risk factors for stroke were recorded and compared between the groups. RESULTS: A total of 265 male patients (95 with sUA 8 mg/dL and 170 with sUA 8 mg/dL) were enrolled. The incidence of ischemic type of stroke was significantly higher in patients with sUA 8 mg/dL (p = 0.038), particularly in the age range of 45-65 years. Multivariate Cox proportional analyses confirmed that age (p = 0.003) and UA (p = 0.019) were major predictive factors for stroke free (ischemic type of stroke) survival. CONCLUSION: Among men with hypertriglyceridemia, the incidence rate of ischemic type of stroke significantly increased with sUA levels 8 mg/dL, particularly in men aged 45 to 65 years. Hyperuricemia is considered a potential predictive factor for ischemic type of stroke and may indicate the need for preventive management in patients with hypertriglyceridemia (Tab. 3, Fig. 1, Ref. 28).
- Subjects
EXERCISE; HEART failure; GENE expression; MOLECULAR genetics; CARDIOVASCULAR diseases; APOPTOSIS
- Publication
Bratislava Medical Journal / Bratislavské Lekárske Listy, 2019, Vol 120, Issue 4, p243
- ISSN
0006-9248
- Publication type
Article
- DOI
10.4149/BLL_2019_044