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- Title
Comparison of Hemodynamic versus Dyssynchrony Assessment for Interventricular Delay Optimization with Echocardiography in Cardiac Resynchronization Therapy.
- Authors
DOLTRA, ADELINA; VIDAL, BÀRBARA; SILVA, ETELVINO; MONT, LLUÍS; TAMBORERO, DAVID; CASTEL, MARÍA ÁNGELES; TOLOSANA, JOSÉ MARÍA; BERRUEZO, ANTONIO; BRUGADA, JOSEP; SITGES, MARTA
- Abstract
Background: Best practice for cardiac resynchronization therapy (CRT) device optimization is not established. This study compared Tissue Doppler Imaging (TDI) to study left ventricular (LV) synchrony and left ventricular outflow tract velocity-time integral (LVOT VTI) to assess hemodynamic performance. Methods: LVOT VTI and LV synchrony were tested in 50 patients at three interventricular (VV) delays (LV preactivation at −30 ms, simultaneous biventricular pacing, and right ventricular preactivation at +30 ms), selecting the highest VTI and the greatest degree of superposition of the displacement curves, respectively, as the optimum VV delay. Results: In 39 patients (81%), both techniques agreed (Kappa = 0.65, p < 0.0001) on the optimum VV delay. LV preactivation (VV − 30) was the interval most frequently chosen. Conclusions: Both TDI and LVOT VTI are useful CRT programming methods for VV optimization. The best hemodynamic response correlates with the best synchrony. In most patients, the optimum VV interval is LV preactivation. (PACE 2011; 34:984-990)
- Subjects
CARDIAC pacing; ECHOCARDIOGRAPHY; ANALYSIS of variance; COMPUTER software; LEFT heart ventricle; HEART failure; HEMODYNAMICS; SCIENTIFIC observation; RESEARCH funding; STATISTICS; DATA analysis
- Publication
Pacing & Clinical Electrophysiology, 2011, Vol 34, Issue 8, p984
- ISSN
0147-8389
- Publication type
Article
- DOI
10.1111/j.1540-8159.2011.03078.x