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- Title
Prevalence, characteristics and prognostic significance of anemia in daily practice.
- Authors
Terrier, B.; Resche-Rigon, M.; Andres, E.; Bonnet, F.; Hachulla, E.; Marie, I.; Rosenthal, E.; Cacoub, P.
- Abstract
Background: The prevalence of anemia has been studied in well-defined populations, but no large study is available for less restricted populations with various disorders.Design: Two-phase nationwide study: (i) a cross-sectional study including 1351 patients aimed to define the prevalence and characteristics of anemic patients seen in France, and (ii) a prospective longitudinal study of 398 anemic patients aimed to define factors associated with survival.Results: Anemia was present in 874 (65%) patients according to WHO criteria, and 573 (42%) patients had hemoglobin levels <110 g/l. Characteristics independently associated with anemia were the presence of cancer, hematological disorder, renal failure and inflammatory syndrome. Baseline factors negatively associated with the 3-month survival were cancer, older age and a lower target hemoglobin level defined at baseline. Negative predictive factors at Month 3 of the 6-month survival were older age and the absence of correction of anemia according to the target hemoglobin level defined at baseline.Conclusion: Anemia is frequent and is associated with cancer, hematological disorders, renal failure and inflammatory syndrome. At baseline, prognostic factors of 3-month survival include cancer, older age and lower target hemoglobin level, whereas reaching the target hemoglobin level at Month 3 has a favorable prognostic impact on 6-month survival.
- Subjects
ANEMIA; DISEASE prevalence; HEMOGLOBINS; KIDNEY failure; INFLAMMATION; MEDICAL statistics; CROSS-sectional method; LONGITUDINAL method
- Publication
QJM: An International Journal of Medicine, 2012, Vol 105, Issue 4, p345
- ISSN
1460-2725
- Publication type
Article
- DOI
10.1093/qjmed/hcr230