We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair.
- Authors
Takebayashi, Yuji; Pourquier, Philippe; Zimonjic, Drazen B.; Nakayama, Kentaro; Emmert, Steffen; Ueda, Takahiro; Urasaki, Yoshimasa; Kanzaki, Atsuko; Akiyama, Shin-ichi; Popescu, Nicholas; Kraemer, Kenneth H.; Pommier, Yves
- Abstract
Studies the antiproliferative activity of ecteinascidin 743, a cancer cell-killing mechanism mediated by DNA nucleotide excision repair (NER). selection of Et743-resistant cell lines; Molecular cytogenetics; XPG complementation of Et743-resistant cells; Mediation of Et743 cytoxicity by transcription-coupled NER.
- Subjects
ANTINEOPLASTIC agents; DNA repair; CYTOGENETICS
- Publication
Nature Medicine, 2001, Vol 7, Issue 8, p961
- ISSN
1078-8956
- Publication type
Article
- DOI
10.1038/91008