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- Title
Quality-of-life issues in survivors to anaphylactic reactions to drugs.
- Authors
Baiardini, I.; Gaeta, F.; Molinengo, G.; Braido, F.; Canonica, G.W.; Romano, A.
- Abstract
The aim of this cross-sectional observational study was to explore quality of life and well-being in patients with drug-induced anaphylaxis. Two validated tools were used: the Drug Hypersensitivity Quality-of-Life Questionnaire (DrHy-Q) and the Psychological General Well-Being Index ( PGWBI). Sixty-five patients (13 males) underwent data analysis. The mean DrHy-Q score was 62.82 ± 12.1. Mean PGWBI score was 64.03 ± 17.66. DrHy-Q score was significantly correlated with PGWBI total score ( r = −0.314; P = 0.011) and with the following domains: Anxiety ( r = −0.260; P = 0.036), Depressed mood ( r = −0.406; P = 0.001), Positive well-being ( r = −0.251; P = 0.004), and General Health ( r = −0.352; P = 0.004). Compared with the Italian reference population, patients had a significantly reduced PGWBI total and domain score. Our results highlight for the first time how impaired HRQoL and distress commonly feature in survivors to anaphylactic reactions to drug.
- Subjects
ANAPHYLAXIS; QUALITY of life; DRUG side effects; QUESTIONNAIRES; DRUG allergy
- Publication
Allergy, 2015, Vol 70, Issue 7, p877
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1111/all.12610