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- Title
Special Issue: Membrane and Receptor Dynamics.
- Authors
Prakash, Shikha; Sengupta, Durba
- Abstract
The issue can be broadly divided into (i) membrane dynamics, (ii) membrane-peptide interactions, (iii) protein dynamics and organization, with a special focus on GPCRs. Membrane fusion and, its seemingly counter phenomenon, fission are areas where membrane dynamics is intricately coupled to protein dynamics, especially to overcome the energy barriers along complicated pathways. Interestingly, in several cases intrinsically disordered proteins and protein regions (IDPRs) do not interact directly with membranes, but they play a major role in regulating the conformational changes in proteins involved in membrane remodeling. Several peptides interact with the membrane by only one of the membrane leaflets but are able to modulate and dictate membrane dynamics in complex ways.
- Subjects
NOGO protein; CELL receptors; MEMBRANE proteins; BILAYER lipid membranes
- Publication
Journal of Membrane Biology, 2019, Vol 252, Issue 4/5, p207
- ISSN
0022-2631
- Publication type
editorial
- DOI
10.1007/s00232-019-00096-z