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- Title
Gut microbiome is not associated with mild cognitive impairment in Parkinson's disease.
- Authors
Aho, Velma T. E.; Klee, Matthias; Landoulsi, Zied; Heintz-Buschart, Anna; Pavelka, Lukas; Leist, Anja K.; Krüger, Rejko; May, Patrick; Wilmes, Paul; Acharya, Geeta; Aguayo, Gloria; Alexandre, Myriam; Ali, Muhammad; Ammerlann, Wim; Arena, Giuseppe; Bassis, Michele; Batutu, Roxane; Beaumont, Katy; Béchet, Sibylle; Berchem, Guy
- Abstract
Gut microbiome differences between people with Parkinson's disease (PD) and control subjects without Parkinsonism are widely reported, but potential alterations related to PD with mild cognitive impairment (MCI) have yet to be comprehensively explored. We compared gut microbial features of PD with MCI (n = 58) to cognitively unimpaired PD (n = 60) and control subjects (n = 90) with normal cognition. Our results did not support a specific microbiome signature related to MCI in PD.
- Subjects
PARKINSON'S disease; MILD cognitive impairment; GUT microbiome; PARKINSONIAN disorders
- Publication
NPJ Parkinson's Disease, 2024, Vol 10, Issue 1, p1
- ISSN
2373-8057
- Publication type
Article
- DOI
10.1038/s41531-024-00687-1