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- Title
Management and Treatment Outcomes of High-Risk Corneal Transplantations.
- Authors
Urbańska, Karolina; Woźniak, Marcin; Więsyk, Piotr; Konarska, Natalia; Bartos, Weronika; Biszewski, Mateusz; Bielak, Michał; Chorągiewicz, Tomasz; Rejdak, Robert
- Abstract
Corneal transplantation is the most effective treatment for corneal blindness. Standard planned keratoplasties have a high success rate. Conditions such as active inflammation at the time of surgery, the presence of ocular surface disease, previous graft disease, or neovascularization make them more susceptible to rejection. These are so-called high-risk corneal transplantations. In our study, we selected 52 patients with a higher risk of graft rejection. A total of 78 procedures were performed. The main indications for the first keratoplasty were infections (59.6%) and traumas (21.2%). Visual acuity (VA) significantly improved from 2.05 logMAR on the day of keratoplasty to 1.66 logMAR in the latest examination (p = 0.003). An analysis of the graft survival showed a 1-year survival of 54% and a 5-year survival of 19.8% of grafts. The mean observation time without complications after the first, second, and third surgery was 23, 13, and 14 months, respectively. The best results were noted among patients with infectious indications for keratoplasty (p = 0.001). Among them, those with bacterial infection had the best visual outcomes (p = 0.047).
- Subjects
CORNEAL transplantation; GRAFT survival; TREATMENT effectiveness; GRAFT rejection; VISUAL acuity; CORNEA surgery
- Publication
Journal of Clinical Medicine, 2022, Vol 11, Issue 19, p5511
- ISSN
2077-0383
- Publication type
Article
- DOI
10.3390/jcm11195511