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- Title
Assessment of Loiasis and Outcomes of Ivermectin Masstreatment in Ijebu-North, Nigeria.
- Authors
Hassan, A. A.; Akinsanya, B.; lyase, N.; Owagboriaye, F. O.
- Abstract
A total of 286 individuals from 3 selected communities (Areedi-Aje, Ipakodo/Ojokodo, and Ijebu-lgbo) of Ijebu-North, southwestern Nigeria were examined for Loa/oa microfilaremia using finger prick blood smear, between December 2008 and March 2009. Rapid assessment procedure for Ioiasis (RAPLOA) was used to obtain information, from 187 Ijebu-Igloo residents, on adverse reactions experienced from retrospective treatments with ivermectin and history of eye worm. Only 33.9% of the respondents reported having had a history of eye worm while 33.2% had microfilaremia. The demo- graphic factor of gender was not significant determinants of the prevalence (P> 0.05) while age was significant (P< 0.05). The highest prevalence of eye worm history and microfilaremia were recorded in 61-70 and 15-20 years of age categories, respectively. Ijebu-lgbo had 27.3% eye worm history, 32.1% microfilaremia, and the highest intensity of 140 microfilariae (mf)/ml. Ipakodo area had the highest eye worm history of 54.4% and the highest intensity of 420 mf/ml. Areedi-Aje had the highest occurrence of 45.2% microfilaremia and the highest intensity of 460 mf/ml. Predictably, Areedi-Aje and Ipakodo areas were high risk communities. The low intensity of L./oa infection with an insignificant (2.1%; P>0.05) adverse reactions from 187 subjects involved in the retrospective ivermectin administration confirmed that ivermectin delivery may be considered safe. The community-directed treatment with ivermectin (CDTI) programme was most probably responsible for the low prevalence and intensity.
- Subjects
IJEBU (Nigeria); NIGERIA; LOAIASIS; IVERMECTIN; IJEBU (African people); BLOOD; FILARIASIS
- Publication
Korean Journal of Parasitology, 2011, Vol 49, Issue 2, p153
- ISSN
0023-4001
- Publication type
Article
- DOI
10.3347/kjp.2011.49.2.153