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- Title
Eosinophil-Mediated Tissue Inflammatory Responses in Helminth Infection.
- Authors
Myeong Heon Shin; Young Ah Lee; Duk-Young Min
- Abstract
Eosinophilic leukocytes function in host protection against parasitic worms. In turn, helminthic parasites harbor specific molecules to evade or paralyze eosinophil-associated host immune responses; these molecules facilitate the migration and survival of parasitic helminths in vivo. This competition between eosinophil and worm leads to stable equilibria between them. An understanding of such dynamic host-eosinophil interactions will help us to uncover mechanisms of cross talk between host and parasite in helminth infection. In this review, we examine recent findings regarding the innate immune responses of eosinophils to helminthic parasites, and discuss the implications of these findings in terms of eosinophil-mediated tissue inflammation in helminth infection.
- Subjects
HELMINTHIASIS; HELMINTH hosts; CROSSTALK; HELMINTHS; EOSINOPHILIA; TISSUES
- Publication
Korean Journal of Parasitology, 2009, Vol 47, pS125
- ISSN
0023-4001
- Publication type
Article
- DOI
10.3347/kjp.2009.47.S.S125