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- Title
Recent advances on cyclodepsipeptides: biologically active compounds for drug research.
- Authors
Si-Xuan Liu; Si-Yi Ou-Yang; Yong-Fu Lu; Chun-Lin Guo; Si-Yang Dai; Chang Li; Tian-Yi Yu; Yue-Hu Pei
- Abstract
Cyclodepsipeptides are a large family of peptide-related natural products consisting of hydroxy and amino acids linked by amide and ester bonds. A number of cyclodepsipeptides have been isolated and characterized from fungi and bacteria. Most of them showed antitumor, antifungal, antiviral, antimalarial, and antitrypanosomal properties. Herein, this review summarizes the recent literatures (2010–2022) on the progress of cyclodepsipeptides from fungi and bacteria except for those of marine origin, in order to enrich our knowledge about their structural features and biological sources.
- Subjects
BIOACTIVE compounds; DOSAGE forms of drugs; HYDROXY acids; NATURAL products; AMINO acids; PEPTIDE antibiotics; ANTIMALARIALS
- Publication
Frontiers in Microbiology, 2023, p1
- ISSN
1664-302X
- Publication type
Article
- DOI
10.3389/fmicb.2023.1276928