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- Title
THE SPASTICITY-RELATED QUALITY OF LIFE 6-DIMENSIONS INSTRUMENT IN UPPER-LIMB SPASTICITY: PART I DEVELOPMENT AND RESPONSIVENESS.
- Authors
TURNER-STOKES, Lynne; FHEODOROFF, Klemens; JACINTO, Jorge; LAMBERT, Jeremy; DE LA LOGE, Christine; CALVI-GRIES, Françoise; WHALEN, John; LYSANDROPOULOS, Andreas; MAISONOBE, Pascal; ASHFORD, Stephen
- Abstract
Objective: To describe the development of the Spasticity-related Quality of Life 6-Dimensions instrument (SQoL-6D) and its sensitivity to clinical change (responsiveness). Design: Multicentre, prospective, longitudinal cohort study at 8 UK sites (NCT03442660). Patients: Adults (n = 104) undergoing focal treatment of upper limb spasticity. Methods: No condition-specific health-related quality of life tool is available for upper-limb spasticity of any aetiology. The SQoL-6D was developed to fulfil this need, designed to complement the Upper Limb Spasticity Index (which incorporates the Goal Attainment Scaling evaluation of upper limb spasticity [GASeous] tool) with targeted standardised measures. The 6 dimensions of the SQoL-6D (score range 0-4) map onto common treatment goal areas identified in upper-limb spasticity studies. A Total score (0-100) provides overall spasticity-related health status. To assess responsiveness, the SQoL-6D, Global Assessment of Benefit scale and "GASeous" were administered at enrolment and 8 weeks. Results: Significant differences in mean SQoL-6D Total score change and effect sizes across patients rating "some benefit" (0.51) and "great benefit" (0.88) supported responsiveness. Conclusion: The SQoL-6D is a promising new measure of health status in upper limb spasticity, that enables systematic assessment of the impact of this condition in relation to patients' priority treatment goals. A psychometric evaluation of SQoL-6D is presented separately.
- Subjects
SPASTICITY diagnosis; RESEARCH; BOTULINUM toxin; MUSCLE relaxants; SPASTICITY; ARM; TREATMENT effectiveness; QUALITY of life; DESCRIPTIVE statistics; RESEARCH funding; DATA analysis software; LONGITUDINAL method
- Publication
Journal of Rehabilitation Medicine (Stiftelsen Rehabiliteringsinformation), 2022, Vol 54, p1
- ISSN
1650-1977
- Publication type
Article
- DOI
10.2340/jrm.v53.690