We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Decrease in High Density Lipoprotein Cholesterol (HDL-C) Levels Following Gemfibrozil Therapy.
- Authors
Lacko, Andras G.; Kudchodkar, Bhalchandra J.; Loney, Wayne W.; Clearfield, Michael B.; Weis, Stephen
- Abstract
This report represents the continuation of our studies on the effects of gemfibrozil therapy on high density lipoprotein cholesterol levels. Previously, we reported that despite an impressive mean increase in high density lipoprotein cholesterol (20 %), the response to 12 weeks of gemfibrozil therapy was highly variable. Accordingly, out of the 27 subjects studied, five actually had lower high density lipoprotein cholesterol at the conclusion of therapy compared to baseline values. The changes observed in plasma lipids, combined with correlational relationships suggest that the conversion of triglyceride rich lipoprotein components into high density lipoprotein may be impaired in those subjects that respond poorly or negatively to gemfibrozil therapy.
- Publication
Clinical Chemistry & Laboratory Medicine, 1998, Vol 36, Issue 6, p389
- ISSN
1434-6621
- Publication type
Article