We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Local Shwartzman activity of lipopolysaccharides from several selected strains of suspected periodontopathic bacteria.
- Authors
Koga, Toshihiko; Chikako Odaka; Moro, Itaru; Fujiwara, Taku; Nishihara, Tatsuji; Okahashi, Nobuo; Hamada, Shlgeyuki
- Abstract
Lipopolysaccharides (LPSs) were isolated from <em>Fusobacterium species, Bacteroides species, Actinobacillus actinomycetemcomitans</em> and <em>Escherichia coli</em> by the phenol water procedure, and their capacity to induce the local Shwartzman reaction was determined. Preparatory and provoking injections of homologous LPS preparations caused LPSs from <em>E. coli</em> and <em>F. nucleatum</em> to induce a hemorrhagic necrosis, indicating a typical Shwartzman reaction. On the other hand, LPSs from <em>A. actinomycetemcomitans</em> and <em>B. gingivalis</em> induced a weak inflammatory lesion, but no necrotic lesion. The provoking activities of LPSs from <em>F. nucleatum</em> and <em>A. actinomycetemcomitans</em> in inducing an inflammatory lesion were comparable to that of LPS from <em>E. coli</em>, but the activity of LPS from <em>B. gingivalis</em> was low. The preparatory activities of LPSs from <em>B. gingivalis</em> and <em>B. oralis</em> in inducing an inflammatory lesion were comparable to those of LPSs from <em>F. nucleatum, F. necrophorum</em> and <em>A. actinomycetemcomitans</em>.
- Subjects
ENDOTOXINS; FUSOBACTERIUM; ACTINOBACILLUS; ESCHERICHIA coli; BIOLOGY techniques; NECROSIS; DRUG administration
- Publication
Journal of Periodontal Research, 1987, Vol 22, Issue 2, p103
- ISSN
0022-3484
- Publication type
Article
- DOI
10.1111/j.1600-0765.1987.tb01547.x