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- Title
Hair Follicle Signaling Networks: A Dermal Papilla-Centric Approach.
- Authors
Ramos, Raul; Guerrero-Juarez, Christian F; Plikus, Maksim V
- Abstract
Functional testing of dermal papilla (DP) signaling inputs into hair follicle (HF) morphogenesis and regeneration is becoming possible with the advent of new Cre lines. Targeted deletion of the signature genes in early DP precursors has revealed significant signaling redundancy during HF morphogenesis. Furthermore, the DP lineage commitment program can be exploited for generating highly inductive DP cells to be used in HF bioengineering assays.
- Subjects
HAIR follicles; HAIR cell regeneration; BIOLOGICAL assay; GENE targeting; CELLULAR signal transduction; MORPHOGENESIS
- Publication
Journal of Investigative Dermatology, 2013, Vol 133, Issue 10, p2306
- ISSN
0022-202X
- Publication type
Article
- DOI
10.1038/jid.2013.262