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- Title
A RARE CLINICAL MANIFESTATION OF GRAVES' DISEASE: EVANS SYNDROME AND A REVIEW OF THE LITERATURE.
- Authors
Calapkulu, M.; Sencar, M. E.; Yıldız, A.; Unsal, I. O.; Cakal, E.
- Abstract
Evans syndrome is a rare combination of autoimmune hemolytic anemia and immune thrombocytopenia. Evans syndrome in cases of Graves' disease is extremely rare. The coexistence of these autoimmune diseases suggests that they may share a common pathogenic pathway. The case here presented is of a 36-year old female patient who was admitted for anemia and thrombocytopenia and was diagnosed with Evans syndrome associated with Graves' disease, and was then treated with methimazole and methylprednisolone (MPSL). During follow-up, MPSL was discontinued gradually over the course of two months. Interestingly, while Evans syndrome is characterized by frequent relapses, this patient has been in remission of Evans syndrome for approximately 1 year without MPSL therapy. The remission of Evans syndrome associated with Graves' disease in the absence of immunosuppressive therapy suggests that these 2 diseases have a common pathogenetic mechanism.
- Subjects
AUTOIMMUNE hemolytic anemia; LITERATURE reviews; DISEASE remission; IDIOPATHIC thrombocytopenic purpura; SYNDROMES; THYROID eye disease; OLDER patients
- Publication
Acta Endocrinologica (1841-0987), 2020, Vol 16, Issue 4, p518
- ISSN
1841-0987
- Publication type
Article
- DOI
10.4183/aeb.2020.518