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- Title
Marginal Zone B-Cell Lymphoma Among Primary B-Cell Lymphoma of Waldeyer's Ring: Histopathologic and Immunohistochemical Study of 16 Tonsillectomy Specimens.
- Authors
Kojima, Masaru; Nakamura, Naoya; Shimizu, Kazuhiko; Tamaki, Yoshio; Itoh, Hideaki; Nakamura, Shigeo
- Abstract
Two subtypes of marginal zone B-cell lymphoma (eg, mucosa-associated lymphoid tissue [MALT] type and splenic type) have been reported in the lymph node. To determine the presence or absence of marginal zone B-cell lymphoma of MALT type and the splenic type among Waldeyer's ring (WR) lymphomas, 16 tonsillectomy specimens were studied. Ten cases (63%) were marginal zone B-cell lymphoma. Among marginal zone B-cell lymphoma, 7 were the MALT type and the remaining 3 cases of marginal zone B-cell lymphoma were the splenic type. Moreover, 4 cases of 7 MALT-type lymphomas contained numerous large cells (diffuse large B-cell lymphoma arising from a low-grade marginal zone B-cell lymphoma of MALT type). The low incidence of primary mucosa-associated lymphoid tissue type lymphoma of WR in previous reports may be because it is difficult to correctly identify the characteristic histologic findings of MALT-type lymphoma because of the small biopsy size.
- Subjects
LYMPHOMAS; B cells; TONSILLECTOMY; HISTOPATHOLOGY; LYMPH nodes
- Publication
International Journal of Surgical Pathology, 2008, Vol 16, Issue 2, p164
- ISSN
1066-8969
- Publication type
Article
- DOI
10.1177/1066896907307039